Mendoza City Center serves up Argentina's wine culture with a side of historic charm. Five leafy plazas connect through pedestrian-friendly streets where locals sip cortados at sidewalk cafés. The neo-Gothic Basilica de San Francisco towers above Plaza Independencia, while art lovers duck into the Municipal Museum of Modern Art between wine tastings. Boutique hotels in converted colonial buildings make perfect home bases for exploring this walkable district. Hop between traditional parrillas serving juicy steaks and wine bars pouring local Malbec. Three metro stations and plenty of taxis make getting around easy, though the best experiences happen on foot under the neighborhood's shady trees.

Mendoza's Historic Center mixes colonial charm with lively urban energy. Stroll the leafy Plaza Independencia to see impressive government buildings and the Metropolitan Cathedral. The pedestrian-only Sarmiento Street buzzes with cafes and shops, while museums showcase pre-earthquake foundations through glass floors. Wine lovers can sample local Malbecs at traditional bars after exploring the Basilica of San Francisco's baroque beauty. Getting around is a breeze with three metro stations nearby and plenty of walkable streets. Traditional parrillas serve up mouthwatering Argentine beef alongside regional wines. Choose from boutique hotels in converted colonial buildings or mid-range options with courtyard gardens to experience the neighborhood's historic character.

Barraquero offers a slice of authentic Argentine life away from Mendoza's tourist hustle. This tree-lined residential neighborhood welcomes travelers into its peaceful rhythm where locals gather in small plazas and backyard asados fill the air with mouthwatering aromas. The nearby Amado Zogbi Winery provides a taste of the region's famous wine culture. Family-run parrillas serve traditional Argentine fare at budget-friendly prices. Guesthouses and hostels in converted homes offer affordable stays with high host interaction. While public transit is limited, taxis are readily available for the short ride to central Mendoza's attractions.

Dorrego delivers an authentic slice of Mendoza life away from the tourist rush. Tree-lined streets create natural green tunnels that shield you from the desert heat. Local wineries like Achaval Ferrer and Amado Zogbi welcome curious sippers right in the neighborhood. Stroll along streets with flowing acequias—those charming irrigation channels that make this desert city feel like an oasis. Family-run restaurants serve up traditional Argentine dishes at prices that won't make your wallet weep. Most places close for siesta, so plan accordingly. Budget-friendly guesthouses and apartment rentals offer a homey base just a 15-minute walk from downtown, with reliable taxis when your feet need a break.