I had a great stay at Palo Santo Hotel last week. The rooms feel very new, sleek, and updated, and there was nice attention to detail, including water dispenser in the lobby, turndown service, and well-designed bathroom. The breakfast service was great, and the front desk staff took the time to learn my name and greet me by sight when arriving in the lobby.
I am sensitive to noise and the street traffic below was a bit loud, but manageable. There are rooms that face their courtyard in the back, which I would imagine would be a bit quieter.
Would absolutely recommend this hotel to others.