Hotels in Seneca

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Tonight
30 Sept - 1 Oct
Tomorrow
1 Oct - 2 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on quality, location and traveller experience. Last updated on .

A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
HK$941
HK$1,035 total
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$967
HK$1,064 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Seneca-Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

3. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
HK$830
HK$913 total
includes taxes & fees
11 Oct - 12 Oct
Tru by Hilton Seneca Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

4. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$734
HK$807 total
includes taxes & fees
28 Oct - 29 Oct
Best Western Seneca-Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

5. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$827
HK$1,029 total
includes taxes & fees
4 Oct - 5 Oct
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

6. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$593
HK$700 total
includes taxes & fees
11 Oct - 12 Oct
Quality Inn Seneca US-123
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$628
HK$690 total
includes taxes & fees
5 Oct - 6 Oct
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A cabin in a forest with a small deck and outdoor seating area.
A wooden interior with a table, chair, and a hanging lantern.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
HK$792
HK$1,217 total
includes taxes & fees
29 Oct - 30 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A golf course with a water body, trees, and a distant view of a bridge.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.
A golf course with a clubhouse, surrounded by dense trees and a large body of water.

9. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
HK$1,169
HK$1,297 total
includes taxes & fees
1 Oct - 2 Oct
Clemson University's James F. Martin Inn
A modern kitchen area with a bar counter and seating.
A vending area with snacks and beverages, including chips and soda.
A modern bar area with high stools and a poolside view.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

10. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
HK$860
HK$955 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn Clemson-University Area
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

11. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
HK$1,459
HK$1,620 total
includes taxes & fees
7 Oct - 8 Oct
The Shepherd Hotel Downtown Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

12. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
HK$1,188
HK$1,319 total
includes taxes & fees
21 Oct - 22 Oct
The Abernathy of Clemson
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.
A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.
A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.
A modern hotel room with a flat-screen TV, a desk with a chair, a kitchenette with a microwave, and a sofa.

13. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
Clemson
HK$1,012
HK$1,123 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Clemson by IHG
A modern bar area with a menu board, bar stools, and a countertop with various items.
A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.
A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.
An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

14. Courtyard Marriott Clemson

Courtyard Marriott Clemson
Clemson
HK$1,052
HK$1,168 total
includes taxes & fees
11 Oct - 12 Oct
Courtyard Marriott Clemson
Room
A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.
A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.
A hotel reception area with two reception desks, a digital screen, and a tiled floor.

15. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
HK$860
HK$955 total
includes taxes & fees
20 Oct - 21 Oct
Comfort Inn & Suites Clemson - University Area
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".
A brick building with a sign reading "The Inn at Patrick Square".
A hotel lobby with a long corridor, seating areas, and a reception desk.

16. The Inn at Patrick Square

The Inn at Patrick Square
Clemson
HK$1,169
HK$1,298 total
includes taxes & fees
4 Oct - 5 Oct
The Inn at Patrick Square
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A hotel room with two beds, a desk, a television, and a clock on the wall.
A wall with a decorative design featuring a building, trees, and a sky with clouds.

17. Inn @ Clemson

Inn @ Clemson
Clemson
HK$572
HK$635 total
includes taxes & fees
4 Oct - 5 Oct
Inn @ Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.
A lobby with seating areas, a reception desk, and a patterned wall.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

18. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
HK$827
HK$918 total
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus Clemson Hotel & Conference Center
A modern hotel lobby with a reception desk, seating area, and a large conference table.
A multi-story hotel with a parking lot in front.
A spacious lobby with a blue carpet, a wooden table with chairs, orange seating, a TV mounted on the wall, and a large arched window with a view.
A snack display with various packaged foods in a store.

19. Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
Anderson
HK$660
HK$732 total
includes taxes & fees
13 Oct - 14 Oct
Microtel Inn & Suites by Wyndham Anderson/Clemson
An outdoor patio area with seating arrangements, including chairs and tables, and a covered section with a view of the street.
A hotel room with a bed, a sofa, a small table, a nightstand with a lamp, and a wall with a forest wallpaper.
A modern kitchen with a large island, dark cabinets, and a view of the city through large windows.
A modern hotel lobby with a central seating area, multiple tables, and a chandelier.

20. Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
Anderson
HK$1,123
HK$1,246 total
includes taxes & fees
18 Oct - 19 Oct
Home2 Suites by Hilton Anderson Downtown
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A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 4 left at
HK$706
per night
HK$827 total
includes taxes & fees
Quality Inn Seneca US-123
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 5 left at
HK$1,091
per night
HK$1,200 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$1,091
per night
HK$1,200 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$973
per night
HK$1,070 total
includes taxes & fees
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$698
per night
HK$768 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 1 left at
HK$1,208
per night
HK$1,329 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A cabin in a forest with a small deck and outdoor seating area.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 1 left at
HK$855
per night
HK$1,286 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 7 left at
HK$659
per night
HK$774 total
includes taxes & fees
Quality Inn Seneca US-123
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
We have 4 left at
HK$1,169
per night
HK$1,286 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 5 left at
HK$1,561
per night
HK$1,718 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
We have 3 left at
HK$1,169
per night
HK$1,286 total
includes taxes & fees
Best Western Seneca-Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A cabin in a forest with a small deck and outdoor seating area.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 2 left at
HK$855
per night
HK$1,286 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$847
per night
HK$932 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 2 left at
HK$1,561
per night
HK$1,718 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 1 left at
HK$1,160
per night
HK$2,553 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
We have 1 left at
HK$1,126
per night
HK$2,478 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$827
per night
HK$1,819 total
includes taxes & fees
Best Western Seneca-Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 1 left at
HK$635
per night
HK$1,495 total
includes taxes & fees
Quality Inn Seneca US-123
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 2 left at
HK$894
per night
HK$1,968 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 8 left at
HK$903
per night
HK$2,232 total
includes taxes & fees
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$734
per night
HK$1,614 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A cabin in a forest with a small deck and outdoor seating area.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
HK$1,875
per night
HK$4,816 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A round wooden table with a flower vase and a WiFi sign, surrounded by blue cushioned benches, in a room with large windows and a hanging light fixture.
Interior
A covered porch with a ceiling fan, a wooden bench, a cushioned sofa, and a small table.
A two-story house with a covered porch, surrounded by a well-maintained lawn and trees.

Screened Patio & Yard: Clemson Weekends/lakes Stay

Screened Patio & Yard: Clemson Weekends/lakes Stay
Seneca
We have 1 left at
HK$1,899
per night
HK$6,553 total
includes taxes & fees
Screened Patio & Yard: Clemson Weekends/lakes Stay
A clear lake with a rocky shoreline and a tree branch overhanging the water.
A two-story building with a garage, a staircase, and a view of the water.
A grassy area with trees and a body of water.
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape
Seneca
We have 1 left at
HK$1,687
per night
HK$5,527 total
includes taxes & fees
6 Mi to South Cove Boat Ramp! Lake Keowee Escape
A rectangular swimming pool with a 3-foot depth marker, surrounded by lounge chairs and a stone wall.
A multi-story residential building with a parking lot in front.
A balcony with a view of a parking lot and houses in the background.
A spacious living room with a wooden dining table, leather sofas, and a ceiling fan.

Condo on Lake Hartwell 3 Mi to Clemson Stadium

Condo on Lake Hartwell 3 Mi to Clemson Stadium
Seneca
We have 1 left at
HK$1,860
per night
HK$5,939 total
includes taxes & fees
Condo on Lake Hartwell 3 Mi to Clemson Stadium
A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.
A covered deck with wooden flooring, outdoor furniture, and a barbecue grill.
A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.
A modern kitchen with stainless steel appliances, white cabinetry, and a central island.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
Seneca
We have 1 left at
HK$1,420
per night
HK$4,972 total
includes taxes & fees
Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
A house with a front porch, a door, and two chairs.
A living room with a sofa, a coffee table, a television, a lamp, a bookshelf, and a ceiling fan.
A two-story house with a garage, surrounded by trees and a well-maintained lawn.
A dining area with a wooden table, chairs, a ceiling fan, and a view of the kitchen through a window.

Clemson Weekends 3 Mi From Memorial Stadium

Clemson Weekends 3 Mi From Memorial Stadium
Seneca
We have 1 left at
HK$2,095
per night
HK$6,984 total
includes taxes & fees
Clemson Weekends 3 Mi From Memorial Stadium
Interior
A kitchen with a central island, bar stools, a brick fireplace, and a stainless steel refrigerator.
A spacious kitchen with white cabinets, a brick backsplash, and a dining area with a long table and chairs.
A wooden staircase with a white railing leading to a second floor.

Historic Farmhouse: Memorable Moments Near Clemson

Historic Farmhouse: Memorable Moments Near Clemson
Seneca
We have 1 left at
HK$5,014
per night
HK$14,726 total
includes taxes & fees
Historic Farmhouse: Memorable Moments Near Clemson
A wooden deck with a metal roof, overlooking a lake and houses.
A modern kitchen with a central island, a dining area with a wooden table and chairs, a grey sofa, and a ceiling fan.
A modern multi-story building with a wooden staircase leading up to a balcony, surrounded by trees.
A wooden bridge leading to a house with a view of a lake.

Lake Keowee Gem! Close to Clemson & Hiking Trails

Lake Keowee Gem! Close to Clemson & Hiking Trails
Seneca
We have 1 left at
HK$4,037
per night
HK$10,940 total
includes taxes & fees
Lake Keowee Gem! Close to Clemson & Hiking Trails

Check out pet-friendly hotels in Seneca

An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
HK$830
HK$913 total
includes taxes & fees
11 Oct - 12 Oct
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$593
HK$700 total
includes taxes & fees
11 Oct - 12 Oct
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$827
HK$1,029 total
includes taxes & fees
4 Oct - 5 Oct
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$628
HK$690 total
includes taxes & fees
5 Oct - 6 Oct
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A cabin in a forest with a small deck and outdoor seating area.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
HK$792
HK$1,217 total
includes taxes & fees
29 Oct - 30 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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You may also like hotels with pools in Seneca

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$827
HK$1,029 total
includes taxes & fees
4 Oct - 5 Oct
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$593
HK$700 total
includes taxes & fees
11 Oct - 12 Oct
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$734
HK$807 total
includes taxes & fees
28 Oct - 29 Oct
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$628
HK$690 total
includes taxes & fees
5 Oct - 6 Oct
Days Inn by Wyndham Seneca / Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
HK$941
HK$1,035 total
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$967
HK$1,064 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Seneca-Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveller single night rates
View properties in September
Typical weather for Seneca
September
High 28°C / low 18°C. Sunny most days.
View properties in September
28°
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6°
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1°
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17°
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Monthly weather averages (˚C)

Top neighbourhoods in Seneca

A lakeside scene with autumn foliage, a clear sky, and a sunset.
A large lake surrounded by dense forests.

Downtown

City centre Seneca charms visitors with well-preserved historical buildings that tell the storey of its railway heritage. The tree-lined Ram Cat Alley showcases local history through colourful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodation range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire city centre is walkable with wide pavements, making it easy to discover this authentic slice of small-town America at your own pace.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Holiday rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The area trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront holiday homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This area is all about authentic lakeside living without commercial distractions. Most travellers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy area in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in holiday rental homes with private yards and driveways. The area gets incredibly quiet after dark—ideal for travellers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
See properties
A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Toy Train Park

Toy Train Park is worth a pic or two when discovering Downtown.
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Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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World of Energy

If museums are on your list of things to see in Seneca, then you might want to head to World of Energy. If you want to experience more of the culture Seneca has to offer, head to Lake Keowee, Keowee Key Golf Course, and High Falls County Park.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A sunset over a lake surrounded by dense forests and residential areas.

Check out reviews of Seneca hotels guests love

Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"Great resort, with all the comforts of home. Close to Clemson University. Hot tub needed heat. Would stay here again."
Christopher 2-night trip
Posted 17 hours ago
Lakeside Lodge Clemson
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"We had a great stay. Nice staff and good breakfast."
Lisa 2-night trip
Posted 2 days ago
Hampton Inn & Suites Seneca-Clemson Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"Staff was great! Room was clean!"
Gretchen 2-night trip
Posted 3 days ago
Tru by Hilton Seneca Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

10/10 Excellent
"Wonderful and clean, we enjoyed our stay"
Michelle 1-night trip
Posted 4 days ago
Fairfield Inn & Suites Seneca Clemson Univ Area
Quality Inn Seneca US-123

Quality Inn Seneca US-123

8/10 Good
"The only issue i had was when I cut the heat on the smoke alarm went off which is understandable but I couldn't use the heat at all"
Lindsay 2-night trip
Posted 4 days ago
Quality Inn Seneca US-123
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"We were in town for parents weekend. Only reasonably priced accommodation. At first I was surprised at how remote the cabins were. But I understand it’s on purpose for people that want to disconnect and enjoy nature. We had no problem finding the place. It was clean. It was cozy. It was an adventure!"
Maria 2-night trip
Posted 7 days ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Best Western Seneca-Clemson

Best Western Seneca-Clemson

8/10 Good
"Na"
William 1-night trip
Posted 2 weeks ago
Best Western Seneca-Clemson

Frequently asked questions

How much does a hotel room cost in Seneca?
You can find top hotels in Seneca from HK$635 with options to suit your budget and needs. If you're after an affordable hotel in Seneca that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Seneca hotels?
Discover great deals on Seneca hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Seneca hotels.
Can I book Seneca hotels with free cancellation?
It's easy to book a refundable Seneca hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some of the best Seneca hotels with free parking?
If you're exploring by car, finding a great Seneca hotel with free parking is a win. Our travellers' favourites include:
Can I book a refundable accommodation option in Seneca?
If you want the flexibility to change your plans to Seneca, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 217 holiday homes. In addition, there are 24 apartments and 13 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 8°C. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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