Hotels in Seneca

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Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
Next weekend
4 Sept - 6 Sept
In two weeks
11 Sept - 13 Sept

Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on comfort, location and traveller experience. Last updated on .

An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
HK$829
HK$912 total
includes taxes & fees
13 Sept - 14 Sept
Tru by Hilton Seneca Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
HK$940
HK$1,034 total
includes taxes & fees
6 Sept - 7 Sept
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$930
HK$1,023 total
includes taxes & fees
3 Sept - 4 Sept
Hampton Inn & Suites Seneca-Clemson Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$593
HK$699 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$854
HK$1,061 total
includes taxes & fees
31 Aug - 1 Sept
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$635
HK$698 total
includes taxes & fees
6 Sept - 7 Sept
Days Inn by Wyndham Seneca / Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$760
HK$836 total
includes taxes & fees
3 Sept - 4 Sept
Best Western Seneca-Clemson
A cabin with a large window, surrounded by trees.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
HK$726
HK$1,144 total
includes taxes & fees
2 Sept - 3 Sept
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern kitchen area with a bar counter and seating.
A modern bar area with high stools and a poolside view.
A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.
A vending area with snacks and beverages, including chips and soda.

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
HK$829
HK$921 total
includes taxes & fees
6 Sept - 7 Sept
Hampton Inn Clemson-University Area
A golf course with a water body, trees, and a distant view of a bridge.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.
A golf course with a clubhouse, surrounded by dense trees and a large body of water.

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
HK$1,168
HK$1,296 total
includes taxes & fees
1 Sept - 2 Sept
Clemson University's James F. Martin Inn
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.

The Abernathy of Clemson

The Abernathy of Clemson
Clemson
HK$1,192
HK$1,324 total
includes taxes & fees
2 Sept - 3 Sept
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
An outdoor patio with wicker furniture, a round table, and a fountain.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
HK$1,761
HK$1,955 total
includes taxes & fees
30 Aug - 31 Aug
The Shepherd Hotel Downtown Clemson
A modern kitchen with a microwave, coffee maker, and bar stools.
A hotel lobby with a reception desk, a large tiger mural, a TV, and a seating area with a blue sofa.
A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.
A Comfort Inn & Suites hotel with a modern design, featuring a prominent sign, well-maintained landscaping, and a clear view of the entrance.

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
HK$826
HK$917 total
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites Clemson - University Area
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A wall with a decorative design featuring a building, trees, and a sky with clouds.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

Inn @ Clemson

Inn @ Clemson
Clemson
HK$597
HK$662 total
includes taxes & fees
30 Aug - 31 Aug
Inn @ Clemson
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
A brick building with a sign reading "The Inn at Patrick Square".
A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".
A hotel lobby with a long corridor, seating areas, and a reception desk.

The Inn at Patrick Square

The Inn at Patrick Square
Clemson
HK$1,168
HK$1,296 total
includes taxes & fees
30 Aug - 31 Aug
The Inn at Patrick Square
A kitchen with a coffee maker, microwave, and refrigerator.
A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.
A red brick building with a white porch and columns, a door, and windows.
A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
HK$600
HK$669 total
includes taxes & fees
27 Sept - 28 Sept
Rodeway Inn & Suites Walhalla
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.
A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
HK$793
HK$880 total
includes taxes & fees
1 Sept - 2 Sept
Best Western Plus Clemson Hotel & Conference Center
A green RV parked in a forest with a picnic table and a covered area.
A living room with a fireplace, sofa, television, and ceiling fan.
A rectangular swimming pool with a tiled deck, surrounded by lounge chairs and umbrellas, and a covered seating area.
A covered outdoor seating area with a table and chairs, large windows, and a wooden lattice fence.

The Point At Lake Hartwell

The Point At Lake Hartwell
Townville
HK$922
HK$1,023 total
includes taxes & fees
30 Aug - 31 Aug
The Point At Lake Hartwell
A poolside area with wicker furniture and a table, surrounded by a fence and greenery.
A Fairfield by Marriott hotel with a modern design, featuring a covered entrance, multiple floors, and a well-lit facade.
A corner market with a wooden interior, a glass door entrance, and a refrigerator display.
A modern lobby with a curved blue sofa, a reception desk, and a bar area.

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
Anderson
HK$726
HK$806 total
includes taxes & fees
6 Sept - 7 Sept
Fairfield Inn & Suites by Marriott Anderson Clemson
A patio area with a round table and chairs, a fire pit, and a building with a stone facade and blue accents.
A modern hotel lobby with a reception desk, seating area, and a large chandelier.
A modern hotel lobby with a long communal table, seating areas, and a TV mounted on the wall.
A modern building with a swimming pool, stone facade, and blue lounge chairs.

Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson
Anderson
HK$1,121
HK$1,244 total
includes taxes & fees
6 Sept - 7 Sept
Residence Inn by Marriott Anderson Clemson
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A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 6 left at
HK$698
per night
HK$818 total
includes taxes & fees
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 6 left at
HK$855
per night
HK$1,061 total
includes taxes & fees
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
HK$1,090
per night
HK$1,199 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$1,090
per night
HK$1,199 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$666
per night
HK$733 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$894
per night
HK$983 total
includes taxes & fees
Best Western Seneca-Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 3 left at
HK$1,168
per night
HK$1,285 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A cabin with a large window, surrounded by trees.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
HK$1,403
per night
HK$1,889 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 3 left at
HK$659
per night
HK$774 total
includes taxes & fees
Quality Inn Seneca US-123
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 2 left at
HK$1,051
per night
HK$1,156 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
We have 4 left at
HK$1,051
per night
HK$1,156 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$855
per night
HK$1,061 total
includes taxes & fees
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$659
per night
HK$724 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 5 left at
HK$1,011
per night
HK$1,113 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$894
per night
HK$983 total
includes taxes & fees
Best Western Seneca-Clemson
A cabin with a large window, surrounded by trees.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 1 left at
HK$855
per night
HK$1,285 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$760
per night
HK$1,672 total
includes taxes & fees
Best Western Seneca-Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 1 left at
HK$685
per night
HK$1,608 total
includes taxes & fees
Quality Inn Seneca US-123
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 1 left at
HK$1,014
per night
HK$2,230 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 3 left at
HK$933
per night
HK$2,302 total
includes taxes & fees
Lakeside Lodge Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
We have 2 left at
HK$1,090
per night
HK$2,398 total
includes taxes & fees
Tru by Hilton Seneca Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$1,172
per night
HK$2,579 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$721
per night
HK$1,587 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a large window, surrounded by trees.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
HK$1,426
per night
HK$3,827 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A clear lake with a rocky shoreline and a tree branch overhanging the water.
A grassy area with trees and a body of water.
A wooden deck with a view of a forested area and a building with a sloped roof.
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape
Seneca
We have 1 left at
HK$1,686
per night
HK$5,523 total
includes taxes & fees
6 Mi to South Cove Boat Ramp! Lake Keowee Escape
A round wooden table with a flower vase and a WiFi sign, surrounded by blue cushioned benches, in a room with large windows and a hanging light fixture.
A covered porch with a ceiling fan, a wooden bench, a cushioned sofa, and a small table.
A two-story house with a covered porch, surrounded by a well-maintained lawn and trees.

Screened Patio & Yard: Clemson Weekends/lakes Stay

Screened Patio & Yard: Clemson Weekends/lakes Stay
Seneca
We have 1 left at
HK$1,897
per night
HK$6,548 total
includes taxes & fees
Screened Patio & Yard: Clemson Weekends/lakes Stay
A living room with a flat-screen TV, wooden entertainment unit, and a ceiling fan.
A modern kitchen with stainless steel appliances, wooden cabinets, and a granite countertop.
A modern kitchen with stainless steel appliances, wooden cabinets, granite countertops, and a built-in oven.
A multi-story residential building with a parking lot in front.

Condo on Lake Hartwell 3 Mi to Clemson Stadium

Condo on Lake Hartwell 3 Mi to Clemson Stadium
Seneca
We have 1 left at
HK$1,756
per night
HK$5,710 total
includes taxes & fees
Condo on Lake Hartwell 3 Mi to Clemson Stadium
A wooden deck with a metal roof, overlooking a lake and houses.
A modern multi-story building with a wooden staircase leading up to a balcony, surrounded by trees.
A kitchen with a wooden table, white cabinets, a microwave, a coffee maker, and a sink.
A modern kitchen with a central island, a dining area with a wooden table and chairs, a grey sofa, and a ceiling fan.

Lake Keowee Gem! Close to Clemson & Hiking Trails

Lake Keowee Gem! Close to Clemson & Hiking Trails
Seneca
We have 1 left at
HK$4,912
per night
HK$12,863 total
includes taxes & fees
Lake Keowee Gem! Close to Clemson & Hiking Trails
A covered patio with wooden chairs and a table, overlooking a fenced yard with a body of water and trees.
A spacious living area with a sofa set, a glass coffee table, and a ceiling fan.
A house with a pathway leading to a dock, surrounded by trees and a body of water.
A two-story house with a dark roof, a garage, and a large rock in the foreground.

Lakefront Seneca Vacation Rental w/ Shared Dock!

Lakefront Seneca Vacation Rental w/ Shared Dock!
Seneca
We have 1 left at
HK$3,097
per night
HK$8,396 total
includes taxes & fees
Lakefront Seneca Vacation Rental w/ Shared Dock!

Check out pet-friendly hotels in Seneca

An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.
A food court with a beverage display, seating area, and a Clemson University sign.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
HK$829
HK$912 total
includes taxes & fees
13 Sept - 14 Sept
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$593
HK$699 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$854
HK$1,061 total
includes taxes & fees
31 Aug - 1 Sept
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$635
HK$698 total
includes taxes & fees
6 Sept - 7 Sept
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a large window, surrounded by trees.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
HK$726
HK$1,144 total
includes taxes & fees
2 Sept - 3 Sept
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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You may also like hotels with pools in Seneca

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
A spacious dining area with a long wooden table and patterned upholstered chairs.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$854
HK$1,061 total
includes taxes & fees
31 Aug - 1 Sept
Lakeside Lodge Clemson
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A reception area with a brick wall, a reception desk, and a glass door leading outside.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$760
HK$836 total
includes taxes & fees
3 Sept - 4 Sept
Best Western Seneca-Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$593
HK$699 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Seneca US-123
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$930
HK$1,023 total
includes taxes & fees
3 Sept - 4 Sept
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lobby with a reception desk, seating area, and a vending machine.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
HK$940
HK$1,034 total
includes taxes & fees
6 Sept - 7 Sept
Fairfield Inn & Suites Seneca Clemson Univ Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$635
HK$698 total
includes taxes & fees
6 Sept - 7 Sept
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveller single night rates
View properties in August
Typical weather for Seneca
August
High 31°C / low 20°C. Sunny most days.
View properties in August
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6°
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Monthly weather averages (˚C)

Top neighbourhoods in Seneca

A large lake surrounded by dense forests.
A lakeside scene with autumn foliage, a clear sky, and a sunset.

Downtown

City centre Seneca charms visitors with well-preserved historical buildings that tell the storey of its railway heritage. The tree-lined Ram Cat Alley showcases local history through colourful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodation range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire city centre is walkable with wide pavements, making it easy to discover this authentic slice of small-town America at your own pace.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Holiday rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The area trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront holiday homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This area is all about authentic lakeside living without commercial distractions. Most travellers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy area in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in holiday rental homes with private yards and driveways. The area gets incredibly quiet after dark—ideal for travellers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Seneca City Hall

Seneca City Hall is worth a pic or two when discovering Downtown.
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Highpointe Lower Field

Highpointe Lower Field is worth a visit, located 5.7 mi (9.1 km) from central Seneca.
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The Gauntlet

If you want to see a show while you're in town, try and grab some tickets at The Gauntlet in Downtown. If you enjoy the show and want to see another, Oconee Community Theatre isn't far.
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Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

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A calm lake with mountains in the background.

Check out reviews of Seneca hotels guests love

Quality Inn Seneca US-123

Quality Inn Seneca US-123

10/10 Excellent
"Convenient location. Reasonably priced. Staff is very friendly and helpful."
Kwanchanok 1-night trip
Posted 2 days ago
Quality Inn Seneca US-123

Frequently asked questions

How much does a hotel room cost in Seneca?
You can find top hotels in Seneca from HK$662 with options to suit your budget and needs. If you're after an affordable hotel in Seneca that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Seneca hotels?
Discover great deals on Seneca hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Seneca hotels.
Can I book Seneca hotels with free cancellation?
It's easy to book a refundable Seneca hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some of the best Seneca hotels with free parking?
If you're exploring by car, finding a great Seneca hotel with free parking is a win. Our travellers' favourites include:
Can I book a refundable accommodation option in Seneca?
If you want the flexibility to change your plans to Seneca, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 218 holiday homes. In addition, there are 21 apartments and 12 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 8°C. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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