Hotels in Seneca

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Check prices for these dates

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on quality, location and traveller experience. Last updated on .

A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern lobby with a reception desk, seating area, and a vending machine.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
HK$942
HK$1,036 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$967
HK$1,064 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A reception area with a brick wall, a reception desk, and a glass door leading outside.

3. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$734
HK$807 total
includes taxes & fees
27 Oct - 28 Oct
Best Western Seneca-Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

4. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$855
HK$1,062 total
includes taxes & fees
26 Oct - 27 Oct
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

5. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$664
HK$780 total
includes taxes & fees
27 Oct - 28 Oct
Quality Inn Seneca US-123
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

6. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$567
HK$624 total
includes taxes & fees
25 Oct - 26 Oct
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.
A wooden interior with a table, chair, and a hanging lantern.

7. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
HK$793
HK$1,217 total
includes taxes & fees
19 Nov - 20 Nov
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
An outdoor patio with wicker furniture, a round table, and a fountain.

8. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
HK$1,427
HK$1,584 total
includes taxes & fees
29 Oct - 30 Oct
The Shepherd Hotel Downtown Clemson
A golf course with a water body, trees, and a distant view of a bridge.
A golf course with a clubhouse, surrounded by dense trees and a large body of water.
A modern building with a central entrance, surrounded by a well-maintained lawn and trees.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

9. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
HK$1,169
HK$1,298 total
includes taxes & fees
22 Oct - 23 Oct
Clemson University's James F. Martin Inn
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.
A conference room with a large round table, multiple chairs, and a projector.
A hotel room with a large bed, bedside tables, a desk with a chair, a TV, and a window with a view.
A gym with exercise equipment, a red medicine ball, and motivational wall text.

10. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
Clemson
HK$1,012
HK$1,124 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Clemson by IHG
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

11. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
HK$1,226
HK$1,361 total
includes taxes & fees
17 Nov - 18 Nov
The Abernathy of Clemson
Room
A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.
A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.
A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.

12. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
HK$827
HK$918 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Clemson - University Area
A modern bar area with a menu board, bar stools, and a countertop with various items.
An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.
A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.
A modern dining area with a bar, bar stools, and a patterned rug.

13. Courtyard Marriott Clemson

Courtyard Marriott Clemson
Clemson
HK$873
HK$969 total
includes taxes & fees
1 Nov - 2 Nov
Courtyard Marriott Clemson
A modern kitchen area with a bar counter and seating.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.
A modern bar area with high stools and a poolside view.
A vending area with snacks and beverages, including chips and soda.

14. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
Clemson
HK$861
HK$955 total
includes taxes & fees
27 Oct - 28 Oct
Hampton Inn Clemson-University Area
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.
A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".
A hotel lobby with a long corridor, seating areas, and a reception desk.

15. The Inn at Patrick Square

The Inn at Patrick Square
Clemson
HK$1,169
HK$1,298 total
includes taxes & fees
26 Oct - 27 Oct
The Inn at Patrick Square
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A hotel room with two beds, a desk, a television, and a clock on the wall.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.
A wall with a decorative design featuring a building, trees, and a sky with clouds.

16. Inn @ Clemson

Inn @ Clemson
Clemson
HK$610
HK$677 total
includes taxes & fees
28 Oct - 29 Oct
Inn @ Clemson
A kitchen with a coffee maker, microwave, and refrigerator.
A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.
A red brick building with a white porch and columns, a door, and windows.
A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.

17. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
Walhalla
HK$627
HK$699 total
includes taxes & fees
19 Nov - 20 Nov
Rodeway Inn & Suites Walhalla
A spacious living room with a fireplace, large windows, and a flat-screen TV mounted above the mantel.
A hotel lobby with a reception desk, potted plants, and a tiled floor.
A spacious hotel dining area with multiple tables and chairs, a large plant, and a television on the wall.
A multi-story hotel with a prominent entrance, a well-lit facade, and a parking area in front.

18. Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
Anderson
HK$861
HK$955 total
includes taxes & fees
8 Nov - 9 Nov
Hilton Garden Inn Anderson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.
A two-story building with a white exterior, a front door, and a balcony.
A dining area with round tables, black chairs, and white tablecloths.

19. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
HK$716
HK$795 total
includes taxes & fees
3 Nov - 4 Nov
Liberty Hall Bed and Breakfast
A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.
A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.
A buffet setup with labeled food stations including cereal, oatmeal, and various hot foods like sausage and omelet.
A laundry room with two stacked washers and dryers, grey tiled walls, and a light-colored floor.

20. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Anderson
HK$863
HK$958 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
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A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$863
per night
HK$950 total
includes taxes & fees
Best Western Seneca-Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 5 left at
HK$1,405
per night
HK$1,545 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$706
per night
HK$777 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 5 left at
HK$855
per night
HK$1,062 total
includes taxes & fees
Lakeside Lodge Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
HK$895
per night
HK$1,330 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 1 left at
HK$785
per night
HK$916 total
includes taxes & fees
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$981
per night
HK$1,079 total
includes taxes & fees
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$67 off
HK$600
per night
HK$660 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$934
per night
HK$1,152 total
includes taxes & fees
Lakeside Lodge Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 1 left at
HK$934
per night
HK$1,373 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 1 left at
HK$3,916
per night
HK$4,308 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
We have 1 left at
HK$1,161
per night
HK$2,553 total
includes taxes & fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$834
per night
HK$1,835 total
includes taxes & fees
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
We have 1 left at
HK$1,141
per night
HK$2,510 total
includes taxes & fees
Hampton Inn & Suites Seneca-Clemson Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
We have 1 left at
HK$664
per night
HK$1,559 total
includes taxes & fees
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
We have 4 left at
HK$855
per night
HK$2,124 total
includes taxes & fees
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$226 off
HK$640
per night
HK$1,409 total
includes taxes & fees
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
We have 5 left at
HK$1,640
per night
HK$4,299 total
includes taxes & fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A rectangular swimming pool with a 3-foot depth marker, surrounded by lounge chairs and a stone wall.
A multi-story residential building with a parking lot in front.
A balcony with a view of a parking lot and houses in the background.
A bedroom with a bed, a nightstand, a lamp, a ceiling fan, and a door leading to a bathroom.

Condo on Lake Hartwell 3 Mi to Clemson Stadium

Condo on Lake Hartwell 3 Mi to Clemson Stadium
Seneca
We have 1 left at
HK$1,177
per night
HK$4,438 total
includes taxes & fees
Condo on Lake Hartwell 3 Mi to Clemson Stadium
A spacious kitchen with a large island, wooden beams, and a stone accent wall.
A wooden staircase with a metal railing, a wooden bench, and a rug leading to a door with frosted glass panels.
A wooden deck with a stone wall, overlooking a forested area.
A modern kitchen with stainless steel appliances, wooden flooring, and a marble countertop.

Lakefront Getaway Dock Fire Pit Kayak Games

Lakefront Getaway Dock Fire Pit Kayak Games
Seneca
We have 1 left at
HK$4,194
per night
HK$12,417 total
includes taxes & fees
Lakefront Getaway Dock Fire Pit Kayak Games
A cozy bedroom with a bed, a nightstand, a lamp, a small table, a window, and a Christmas tree.
A living room with a sofa, ottoman, and a leather chair with a 'Family' pillow. There is a ceiling fan, a plant, and a window with curtains.
A kitchen with wooden cabinets, a microwave, a stove, and a refrigerator.
A home interior with a metal shelf unit displaying various items, a hallway with wooden flooring, and a door leading to another room.

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
Seneca
We have 1 left at
HK$1,468
per night
HK$4,813 total
includes taxes & fees
8 Mi to Clemson: Peaceful Family Home w/ Yard
A clear lake with a rocky shoreline and a tree branch overhanging the water.
A two-story building with a garage, a staircase, and a view of the water.
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.
A grassy area with trees and a body of water.

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

6 Mi to South Cove Boat Ramp! Lake Keowee Escape
Seneca
We have 1 left at
HK$1,687
per night
HK$5,529 total
includes taxes & fees
6 Mi to South Cove Boat Ramp! Lake Keowee Escape
A round wooden table with a flower vase and a WiFi sign, surrounded by blue cushioned benches, in a room with large windows and a hanging light fixture.
A two-story house with a covered porch, surrounded by a well-maintained lawn and trees.
Interior
A covered porch with a flag, a tree, and a house entrance.

Screened Patio & Yard: Clemson Weekends/lakes Stay

Screened Patio & Yard: Clemson Weekends/lakes Stay
Seneca
We have 1 left at
HK$1,899
per night
HK$6,555 total
includes taxes & fees
Screened Patio & Yard: Clemson Weekends/lakes Stay
A cozy cabin interior with a dining area, kitchen, and living space.
A cabin with a gravel driveway, a wooden deck, and a view of a lake surrounded by trees.
A wooden cabin kitchen with a granite countertop, stainless steel appliances, and a clock on the wall.
A cozy wooden cabin bedroom with a bed, dresser, and ceiling fan.

Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!

Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!
Seneca
We have 1 left at
HK$1,562
per night
HK$4,492 total
includes taxes & fees
Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!
A four-poster bed with a white bedspread and pillows, a nightstand with a lamp and a fan, a chair, and a colorful rug.
A modern kitchen with white cabinets, a stainless steel refrigerator, and a built-in oven.
A living room with a sofa, a desk with a computer, a green chair, and a painting on the wall.
A covered outdoor seating area with a sofa, a glass-top coffee table, and a barbecue grill.

Clemson Basecamp! Lake Keowee Hideaway

Clemson Basecamp! Lake Keowee Hideaway
Seneca
We have 1 left at
HK$2,668
per night
HK$8,828 total
includes taxes & fees
Clemson Basecamp! Lake Keowee Hideaway
A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.
A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.
Interior
A modern kitchen with stainless steel appliances, white cabinetry, and a central island.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
Seneca
We have 1 left at
HK$1,421
per night
HK$4,973 total
includes taxes & fees
Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Check out pet-friendly hotels in Seneca

An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
HK$830
HK$913 total
includes taxes & fees
8 Nov - 9 Nov
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$664
HK$780 total
includes taxes & fees
27 Oct - 28 Oct
Quality Inn Seneca US-123
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$855
HK$1,062 total
includes taxes & fees
26 Oct - 27 Oct
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$567
HK$624 total
includes taxes & fees
25 Oct - 26 Oct
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
Private kitchen
A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.
A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
HK$793
HK$1,217 total
includes taxes & fees
19 Nov - 20 Nov
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
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You may also like hotels with pools in Seneca

A hotel dining area with a long table, multiple chairs, and a bar in the background.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A reception area with a counter, chairs, and a patterned rug.

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
HK$967
HK$1,064 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
HK$942
HK$1,036 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
HK$734
HK$807 total
includes taxes & fees
27 Oct - 28 Oct
Best Western Seneca-Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
HK$855
HK$1,062 total
includes taxes & fees
26 Oct - 27 Oct
Lakeside Lodge Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
HK$664
HK$780 total
includes taxes & fees
27 Oct - 28 Oct
Quality Inn Seneca US-123
A modern dining area with a high ceiling, large windows, and a buffet setup.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
HK$567
HK$624 total
includes taxes & fees
25 Oct - 26 Oct
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveller single night rates
View properties in October
Typical weather for Seneca
October
High 23°C / low 12°C. Sunny most days.
View properties in October
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17°
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Monthly weather averages (˚C)

Top neighbourhoods in Seneca

A lakeside scene with autumn foliage, a clear sky, and a sunset.
A large lake surrounded by dense forests.

Downtown

City centre Seneca charms visitors with well-preserved historical buildings that tell the storey of its railway heritage. The tree-lined Ram Cat Alley showcases local history through colourful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodation range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire city centre is walkable with wide pavements, making it easy to discover this authentic slice of small-town America at your own pace.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Holiday rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The area trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront holiday homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This area is all about authentic lakeside living without commercial distractions. Most travellers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy area in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in holiday rental homes with private yards and driveways. The area gets incredibly quiet after dark—ideal for travellers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
See properties
A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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World of Energy

If museums are on your list of things to see in Seneca, then you might want to head to World of Energy. If you want to experience more of the culture Seneca has to offer, head to Lake Keowee, Keowee Key Golf Course, and High Falls County Park.
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South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.
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Highpointe Lower Field

Highpointe Lower Field is worth a visit, located 5.7 mi (9.1 km) from central Seneca.
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Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.
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Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.
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Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.
See properties

Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

See all hotels in Seneca
A sunset over a lake surrounded by dense forests and residential areas.

Check out reviews of Seneca hotels guests love

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"Room was clean and staff was friendly and helpful."
Sasha 1-night trip
Posted 12 hours ago
Hampton Inn & Suites Seneca-Clemson Area
Quality Inn Seneca US-123

Quality Inn Seneca US-123

10/10 Excellent
"Hotel was very clean and staff was very very pleasant."
ashlee 2-night trip
Posted 1 day ago
Quality Inn Seneca US-123
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

8/10 Good
"A nice variety for breakfast."
Angela 2-night trip
Posted 3 days ago
Fairfield Inn & Suites Seneca Clemson Univ Area
Best Western Seneca-Clemson

Best Western Seneca-Clemson

10/10 Excellent
"Property was very clean, well maintained, quiet, and close to our ball tournament location. Great value stay. Breakfast was really good and staff were very friendly and helpful."
Andrea 1-night trip
Posted 3 days ago
Best Western Seneca-Clemson
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Very clean, had every thing you needed for a good trip. Wish they had some board games in the cabin but everything else was great."
Anonymous traveller 1-night trip
Posted 3 days ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"The staff were very friendly and everything was nice and clean! A great selection for breakfast!"
Alexis 2-night trip
Posted 6 days ago
Tru by Hilton Seneca Clemson

Frequently asked questions

How much does a hotel room cost in Seneca?
You can find top hotels in Seneca from HK$624 with options to suit your budget and needs. If you're after an affordable hotel in Seneca that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Seneca hotels?
Discover great deals on Seneca hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Seneca hotels.
Can I book Seneca hotels with free cancellation?
It's easy to book a refundable Seneca hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some of the best Seneca hotels with free parking?
If you're exploring by car, finding a great Seneca hotel with free parking is a win. Our travellers' favourites include:
Can I book a refundable accommodation option in Seneca?
If you want the flexibility to change your plans to Seneca, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 217 holiday homes. In addition, there are 24 apartments and 13 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 8°C. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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