Hotels in Cape Girardeau

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Where to stay in Cape Girardeau?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on 4 November 2026.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,000 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Centre.
The price is HK$785
HK$885 total
includes taxes & fees
18 Nov - 19 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness centre, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is HK$777
HK$884 total
includes taxes & fees
2 Dec - 3 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Centre with free WiFi and parking.
The price is HK$706
HK$797 total
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites Cape Girardeau

4. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (857 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness centre, or relax on the terrace after exploring nearby aquatic attractions.
The price is HK$766
HK$864 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn Cape Girardeau I 55 East

5. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (240 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Centre.
The price is HK$794
HK$895 total
includes taxes & fees
19 Nov - 20 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau

6. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (700 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is HK$870
HK$981 total
includes taxes & fees
9 Nov - 10 Nov
The Riverview

7. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (556 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this city centre Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness centre after visiting nearby Riverfront Park and Isle Casino.
The price is HK$911
HK$1,032 total
includes taxes & fees
22 Nov - 23 Nov
Courtyard by Marriott Cape Girardeau Downtown

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,000 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Centre and Conservation Nature Centre. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is HK$565
HK$637 total
includes taxes & fees
8 Nov - 9 Nov
Pear Tree Inn Cape Girardeau West

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness centre.
The price is HK$669
HK$762 total
includes taxes & fees
18 Nov - 19 Nov
Tru By Hilton Cape Girardeau

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
The price is HK$557
HK$672 total
includes taxes & fees
22 Nov - 23 Nov
Candlewood Suites Cape Girardeau by IHG

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (816 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is HK$466
HK$526 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn Cape Girardeau North

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, Good, (243 reviews)
Wake up to adventure at this Cape Girardeau motel near the Family Aquatic Centre and Show Me Centre. Enjoy hassle-free travel with free WiFi, complimentary parking, and 24-hour front desk service for your Missouri getaway.
The price is HK$549
HK$642 total
includes taxes & fees
5 Nov - 6 Nov
Town House Inn Cape Giradreau

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (890 reviews)
The price is HK$627
HK$679 total
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

14. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,003 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is HK$628
HK$664 total
includes taxes & fees
29 Nov - 30 Nov
Drury Inn & Suites Jackson MO

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
Begin your day with a complimentary breakfast at this Jackson hotel near Mississippi River and Shawnee National Forest. The indoor pool offers year-round swimming while free WiFi and parking add value. Cape Girardeau Conservation Nature Centre awaits nearby.
The price is HK$594
HK$642 total
includes taxes & fees
24 Nov - 25 Nov
Comfort Suites Jackson-Cape Girardeau

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
Adventure seekers can explore nearby hiking trails, kayaking, and rafting, then return to this welcoming hotel. Enjoy free continental breakfast, WiFi, and parking, plus exceptional service from the staff that guests consistently praise.
The price is HK$825
HK$898 total
includes taxes & fees
11 Nov - 12 Nov
EC Reed's Mercantile and Hotel

17. Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (41 reviews)
Tucked near a train station in Makanda, this B&B offers a tranquil escape with massage services and a welcoming bar. Explore nearby Makanda Boardwalk after breakfast, then unwind on the terrace as forest sounds serenade your evening.
The price is HK$2,035
HK$2,320 total
includes taxes & fees
5 Nov - 6 Nov
Makanda Inn

18. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (450 reviews)
Feel welcomed at this cosy motel with friendly service just minutes from Shawnee National Forest. Enjoy convenient perks including complimentary WiFi and parking, plus easy access to Litz Park and Lazy L Safari Park for outdoor adventures.
The price is HK$621
HK$673 total
includes taxes & fees
5 Nov - 6 Nov
Town House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out pet-friendly hotels in Cape Girardeau

You can also stay at hotels with a pool in Cape Girardeau

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Go beyond your typical stay in Cape Girardeau

When is the best time to visit Cape Girardeau?

Our prices for hotels in Cape Girardeau are cheapest in December

Price trends for hotels in Cape Girardeau

Pricing is based on two traveller single night rates
View properties in November
Currently viewing crowd sizes and weather for November.

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Top landmarks in Cape Girardeau

Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

A nighttime view of a bridge with its cables illuminated against a starry sky.

Frequently Asked Questions

How much does a hotel room cost in Cape Girardeau?

You can choose a great hotel in Cape Girardeau from HK$466 with properties to suit all budgets and needs. Pear Tree Inn Cape Girardeau West is one low-cost option that's popular with our travellers. If you're looking for an affordable hotel in Cape Girardeau that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Cape Girardeau hotels?

Discover great deals on Cape Girardeau hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Cape Girardeau hotels.

Can I book Cape Girardeau hotels with free cancellation?

In order to book a refundable Cape Girardeau hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some top pet-friendly hotels in Cape Girardeau?

Our travellers' favourite pet-friendly hotels in Cape Girardeau include:

You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Cape Girardeau.

What are some of the best hotels in Cape Girardeau for couples?

Choose a top-rated Cape Girardeau romantic hotel and enjoy your couple's getaway. Our travellers love The Riverview, a hotel with 2 restaurants as well as champagne service. Discover more hotels in Cape Girardeau on Hotels.com for couples by using the "Traveller experience" filter in your search and selecting "Adults only" or "Romantic".

What are some of the best kid-friendly hotels in Cape Girardeau?

One of the best Cape Girardeau hotels for kids is Drury Plaza Hotel Cape Girardeau Conference Center. Drury Plaza Hotel Cape Girardeau Conference Center is a kid-friendly hotel with a guest score of 9.6 out of 10 offering family-friendly amenities like an indoor pool and a hot tub, plus free cots in guestrooms. Find even more kid-friendly hotels in Cape Girardeau by using our "Family friendly" filter on Hotels.com when you search.

What are the top Cape Girardeau hotels with a pool?

For some added luxury, discover the best Cape Girardeau hotels with a pool. Drury Plaza Hotel Cape Girardeau Conference Center is a great hotel with an indoor pool and a guest rating of 9.6 out of 10. Drury Inn & Suites Cape Girardeau is a popular hotel that features an indoor pool along with a hot tub and a free buffet breakfast. To find more stays in Cape Girardeau with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".

What are some of the best Cape Girardeau hotels with free parking?

If you're exploring by car, finding a great Cape Girardeau hotel with free parking is a win. Our travellers' favourites include:

What are some popular hotels in central Cape Girardeau?

For hotels in central Cape Girardeau, check out Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown. Travellers love Drury Plaza Hotel Cape Girardeau Conference Center for its location, as well as the indoor pool, hot tub and restaurant this hotel offers. Courtyard by Marriott Cape Girardeau Downtown is another popular central hotel with a restaurant, a bar/lounge and a coffee shop/cafe.