Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on .
Hotels in Cape Girardeau
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18 Sept - 19 SeptTomorrow
19 Sept - 20 SeptThis weekend
18 Sept - 20 SeptNext weekend
25 Sept - 27 SeptWhere to stay in Cape Girardeau?
1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
HK$792
HK$902 total
includes taxes & fees
27 Sept - 28 Sept
2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$784
HK$885 total
includes taxes & fees
28 Sept - 29 Sept
3. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
HK$981
HK$1,112 total
includes taxes & fees
11 Oct - 12 Oct
4. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
HK$830
HK$936 total
includes taxes & fees
27 Sept - 28 Sept
5. The Riverview
The RiverviewCape Girardeau
HK$852
HK$961 total
includes taxes & fees
21 Sept - 22 Sept
6. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
HK$565
HK$637 total
includes taxes & fees
28 Sept - 29 Sept
7. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
HK$706
HK$797 total
includes taxes & fees
24 Sept - 25 Sept
8. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
HK$794
HK$895 total
includes taxes & fees
24 Sept - 25 Sept
9. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
HK$701
HK$798 total
includes taxes & fees
11 Oct - 12 Oct
10. Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
HK$466
HK$526 total
includes taxes & fees
27 Sept - 28 Sept
11. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
HK$690
HK$822 total
includes taxes & fees
4 Oct - 5 Oct
12. Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
HK$588
HK$687 total
includes taxes & fees
26 Sept - 27 Sept
13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
HK$660
HK$715 total
includes taxes & fees
21 Sept - 22 Sept
14. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
HK$667
HK$705 total
includes taxes & fees
23 Sept - 24 Sept
15. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
HK$593
HK$642 total
includes taxes & fees
11 Oct - 12 Oct
16. Town House Inn
Town House InnJackson
HK$537
HK$581 total
includes taxes & fees
20 Sept - 21 Sept
17. Makanda Inn
Makanda InnMakanda
HK$2,014
HK$2,296 total
includes taxes & fees
30 Sept - 1 Oct
18. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
HK$792
HK$862 total
includes taxes & fees
21 Sept - 22 Sept
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HK$910
per night
HK$1,027 total
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
We have 1 left at
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGHK$1,090
per night
HK$1,241 total
includes taxes & fees
HK$787
per night
HK$931 total
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$1,216
per night
HK$1,372 total
includes taxes & fees
We have 1 left at
Hampton Inn Cape Girardeau I 55 EastHK$1,130
per night
HK$1,274 total
includes taxes & fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
We have 3 left at
Fairfield Inn & Suites by Marriott Cape GirardeauHK$1,169
per night
HK$1,319 total
includes taxes & fees
We have 5 left at
Drury Inn & Suites Cape GirardeauHK$1,137
per night
HK$1,283 total
includes taxes & fees
We have 1 left at
Tru By Hilton Cape GirardeauHK$1,090
per night
HK$1,241 total
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
We have 1 left at
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGHK$1,369
per night
HK$3,116 total
includes taxes & fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
We have 1 left at
Fairfield Inn & Suites by Marriott Cape GirardeauHK$1,269
per night
HK$2,864 total
includes taxes & fees
We have 8 left at
Hampton Inn Cape Girardeau I 55 EastHK$1,324
per night
HK$2,987 total
includes taxes & fees
HK$1,075
per night
HK$2,511 total
includes taxes & fees
HK$1,339
per night
HK$3,048 total
includes taxes & fees
We have 7 left at
Pear Tree Inn Cape Girardeau WestHK$1,310
per night
HK$2,956 total
includes taxes & fees
We have 4 left at
Drury Inn & Suites Cape GirardeauHK$1,565
per night
HK$3,531 total
includes taxes & fees
We have 1 left at
Town House Inn Cape GiradreauHK$588
per night
HK$1,375 total
includes taxes & fees
HK$828
per night
HK$1,868 total
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
We have 1 left at
Drury Plaza Hotel Cape Girardeau Conference CenterHK$1,926
per night
HK$4,345 total
includes taxes & fees
Check out pet-friendly hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$784
HK$885 total
includes taxes & fees
28 Sept - 29 Sept
HK$706
HK$797 total
includes taxes & fees
24 Sept - 25 Sept
HK$565
HK$637 total
includes taxes & fees
28 Sept - 29 Sept
HK$830
HK$936 total
includes taxes & fees
27 Sept - 28 Sept
HK$701
HK$798 total
includes taxes & fees
11 Oct - 12 Oct
HK$690
HK$822 total
includes taxes & fees
4 Oct - 5 Oct
HK$588
HK$687 total
includes taxes & fees
26 Sept - 27 Sept
You may also like hotels with pools in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$784
HK$885 total
includes taxes & fees
28 Sept - 29 Sept
HK$706
HK$797 total
includes taxes & fees
24 Sept - 25 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
HK$792
HK$902 total
includes taxes & fees
27 Sept - 28 Sept
HK$830
HK$936 total
includes taxes & fees
27 Sept - 28 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
HK$794
HK$895 total
includes taxes & fees
24 Sept - 25 Sept
HK$701
HK$798 total
includes taxes & fees
11 Oct - 12 Oct
HK$690
HK$822 total
includes taxes & fees
4 Oct - 5 Oct
HK$466
HK$526 total
includes taxes & fees
27 Sept - 28 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Cape Girardeau
Pet friendly
Family friendly
Our prices for hotels in Cape Girardeau are cheapest in December
Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveller single night rates
Top landmarks in Cape Girardeau
Southeast Missouri State University
8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
Riverfront Bridge Park
8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay?
Hunter Valley Winery
7.4/10 (48 reviews)
Travellers might want a tour of Hunter Valley Winery, just one of the places to visit, located 9.3 mi (14.9 km) from central Cape Girardeau.
Show Me Center
8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
Riverfront Park
8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
Cape Splash Family Aquatic Center
8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau? If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
Cape Rock Park
8.6/10 (36 reviews)
Cape Rock Park is worth a visit, located 1.9 mi (3.1 km) from central Cape Girardeau.
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.
See all hotels in Cape Girardeau
Check out reviews of Cape Girardeau hotels guests love
The Riverview
8/10 Good
"Nice room and friendly staff. Everything was great except for the bathroom having a sliding door which provides less privacy. Also the mini refrigerator wasnt very cold even when on the coldest setting. Other than that zero complaints."
Tru By Hilton Cape Girardeau
10/10 Excellent
"The staff is always super kind and helpful"
Quality Inn Cape Girardeau North
8/10 Good
"No complaints"
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"I was there overnight while I visited a family member. Everything was fine. People were friendly."
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Excellent breakfast,friendly staff and clean rooms"
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"The receptionist was very courteous. Helped answer all my questions. We loved the room. And we had a great breakfast before we left."
Town House Inn Cape Giradreau
8/10 Good
"The outside needed cleaning, but the room was very clean and well maintained."