Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on comfort, location and traveller experience. Last updated on .
Hotels in Cape Girardeau
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Check prices for these dates
Tonight
25 Aug - 26 AugTomorrow
26 Aug - 27 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sept - 6 SeptTop 5 hotels in Cape Girardeau at a glance
- Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG — 2.5-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
- Courtyard by Marriott Cape Girardeau Downtown — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
- Pear Tree Inn Cape Girardeau West — 2.5-star hotel in Cape Girardeau. Guest rating: 9.0/10 — Wonderful.
- Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
Where to stay in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$784
HK$884 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
HK$799
HK$902 total
includes taxes & fees
22 Sept - 23 Sept
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
HK$980
HK$1,111 total
includes taxes & fees
6 Sept - 7 Sept
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
HK$564
HK$636 total
includes taxes & fees
31 Aug - 1 Sept
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
HK$705
HK$796 total
includes taxes & fees
2 Sept - 3 Sept
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
HK$829
HK$935 total
includes taxes & fees
1 Sept - 2 Sept
The Riverview
The RiverviewCape Girardeau
HK$851
HK$960 total
includes taxes & fees
27 Aug - 28 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
HK$793
HK$894 total
includes taxes & fees
6 Sept - 7 Sept
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
HK$700
HK$797 total
includes taxes & fees
6 Sept - 7 Sept
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
HK$690
HK$821 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
HK$484
HK$546 total
includes taxes & fees
6 Sept - 7 Sept
Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
HK$549
HK$641 total
includes taxes & fees
5 Sept - 6 Sept
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
HK$651
HK$688 total
includes taxes & fees
30 Aug - 31 Aug
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
HK$693
HK$750 total
includes taxes & fees
26 Aug - 27 Aug
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
HK$700
HK$757 total
includes taxes & fees
1 Sept - 2 Sept
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
HK$751
HK$818 total
includes taxes & fees
26 Aug - 27 Aug
Makanda Inn
Makanda InnMakanda
HK$2,012
HK$2,293 total
includes taxes & fees
27 Aug - 28 Aug
Hotel 7 Inn Anna
Hotel 7 Inn AnnaAnna
HK$550
HK$638 total
includes taxes & fees
26 Aug - 27 Aug
Check out pet-friendly hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$784
HK$884 total
includes taxes & fees
6 Sept - 7 Sept
HK$564
HK$636 total
includes taxes & fees
31 Aug - 1 Sept
HK$705
HK$796 total
includes taxes & fees
2 Sept - 3 Sept
HK$829
HK$935 total
includes taxes & fees
1 Sept - 2 Sept
HK$700
HK$797 total
includes taxes & fees
6 Sept - 7 Sept
HK$690
HK$821 total
includes taxes & fees
6 Sept - 7 Sept
HK$549
HK$641 total
includes taxes & fees
5 Sept - 6 Sept
You may also like hotels with pools in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
HK$784
HK$884 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
HK$799
HK$902 total
includes taxes & fees
22 Sept - 23 Sept
HK$705
HK$796 total
includes taxes & fees
2 Sept - 3 Sept
HK$829
HK$935 total
includes taxes & fees
1 Sept - 2 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
HK$793
HK$894 total
includes taxes & fees
6 Sept - 7 Sept
HK$700
HK$797 total
includes taxes & fees
6 Sept - 7 Sept
HK$690
HK$821 total
includes taxes & fees
6 Sept - 7 Sept
HK$484
HK$546 total
includes taxes & fees
6 Sept - 7 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Cape Girardeau
Pet friendly
Family friendly
Our prices for hotels in Cape Girardeau are cheapest in December
Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveller single night rates
Top landmarks in Cape Girardeau
Southeast Missouri State University
8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
Riverfront Bridge Park
8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay?
Hunter Valley Winery
7.4/10 (48 reviews)
Travellers might want a tour of Hunter Valley Winery, just one of the places to visit, located 9.3 mi (14.9 km) from central Cape Girardeau.
Riverfront Park
8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
Show Me Center
8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
Cape Splash Family Aquatic Center
8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau? If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
Cape Rock Park
8.6/10 (36 reviews)
Cape Rock Park is worth a visit, located 1.9 mi (3.1 km) from central Cape Girardeau.
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.
See all hotels in Cape Girardeau
Check out reviews of Cape Girardeau hotels guests love
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Very nice hotel......................"
Tru By Hilton Cape Girardeau
10/10 Excellent
"We had a great stay at Tru in Cape. The hotel was clean, comfortable, and the staff made everything easy. The only thing missing was having microwaves in the rooms — adding those would make the experience even better."
Drury Inn & Suites Cape Girardeau
10/10 Excellent
"The staff at the location were very accommodating. Check to make sure everything was good. The breakfast was awesome. I was concerned that the pool was being under construction and that was not sent out to people that are planning or had planned to stay there. I was looking forward to the pool and if have been a hot tub."
Courtyard by Marriott Cape Girardeau Downtown
8/10 Good
"Hotel was nice, my bathroom felt a bit outdated. Outside of that it was a great stay"
The Riverview
8/10 Good
"Nice view of the river. The staff was nice."
Town House Inn Cape Giradreau
10/10 Excellent
"If your looking for a budget friendly hotel to stay that is clean or if you need a place to call home for a month till you find a place, I highly recommend this hotel."
Hampton Inn Cape Girardeau I 55 East
10/10 Excellent
"Good Job!"