Hotels in Sanctuary

Free cancellation options if plans change

Unlock travel rewards with One Key

Save more with Member Prices

Check prices for these dates

Tonight
Dec 11 - Dec 12
Tomorrow
Dec 12 - Dec 13
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Where to stay in Sanctuary?

Lobby
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
2.3 mi from Sanctuary
8.6 out of 10, Excellent, (1001)
$299 nightly
The price is $333
Dec 25 - Dec 26
Total with taxes and fees
Tween Waters Island Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See more propertiesforward arrow

When is the best time to visit Sanibel?

Our prices for hotels in Sanibel are cheapest in September
Price trends for hotels in Sanibel
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Sanibel
December
Low crowds
High 74°F / low 64°F. Sunny most days.
View properties in December
74°
weather_sun
December, Low crowds, average high temperature 74 degrees Fahrenheit, average low temperature 64 degrees Fahrenheit. Sunny most days.
64°
70°
weather_sun
January, Moderate crowds, average high temperature 70 degrees Fahrenheit, average low temperature 60 degrees Fahrenheit. Sunny most days.
60°
73°
weather_sun
February, High crowds, average high temperature 73 degrees Fahrenheit, average low temperature 62 degrees Fahrenheit. Sunny most days.
62°
76°
weather_sun
March, High crowds, average high temperature 76 degrees Fahrenheit, average low temperature 64 degrees Fahrenheit. Sunny most days.
64°
80°
weather_sun
April, High crowds, average high temperature 80 degrees Fahrenheit, average low temperature 70 degrees Fahrenheit. Sunny most days.
70°
84°
weather_sun
May, High crowds, average high temperature 84 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Sunny most days.
74°
86°
weather_partly_sunny
June, Moderate crowds, average high temperature 86 degrees Fahrenheit, average low temperature 78 degrees Fahrenheit. Partly sunny.
78°
88°
weather_partly_sunny
July, Moderate crowds, average high temperature 88 degrees Fahrenheit, average low temperature 80 degrees Fahrenheit. Partly sunny.
80°
88°
weather_partly_sunny
August, Moderate crowds, average high temperature 88 degrees Fahrenheit, average low temperature 80 degrees Fahrenheit. Partly sunny.
80°
87°
weather_partly_sunny
September, Low crowds, average high temperature 87 degrees Fahrenheit, average low temperature 78 degrees Fahrenheit. Partly sunny.
78°
83°
weather_sun
October, Low crowds, average high temperature 83 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Sunny most days.
74°
78°
weather_sun
November, Low crowds, average high temperature 78 degrees Fahrenheit, average low temperature 68 degrees Fahrenheit. Sunny most days.
68°
Monthly weather averages (˚F)

Check out reviews of Sanctuary hotels guests love

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

10/10 Excellent
"The lady at check in was excellent. Friendly, kind and informative. Many thanks."
Sue 1-night trip
Posted 1 day ago
The Westin Cape Coral Resort At Marina Village

Frequently asked questions

Is Sanctuary expensive to stay in?
You can find great hotels from $106 in Sanctuary to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Sanctuary hotels?
Discover great deals on hotels in Sanctuary with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Sanctuary hotels.
Can I receive a refund if I cancel my Sanctuary hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Sanctuary hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Sanctuary?
There are 12 hotels in the area to find your perfect somewhere. Basing yourself in Sanctuary makes it easy to explore Sanibel, including the neighborhoods of West End and Gulf Shores.
Find out more about Sanctuary

Keep exploring