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Hotels in Guadalupe District

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Dec 23 - Dec 24
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Dec 24 - Dec 25
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Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Where to stay in Guadalupe District?

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Guadalupe Inn

Guadalupe Inn

Guadalupe Inn
2.0 star property
Guadalupe District
9.2 out of 10, Wonderful, (1000)
$88 nightly
The price is $101
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guadalupe Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Santa Fe?

Our prices for hotels in Santa Fe are cheapest in January
Price trends for hotels in Santa Fe
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Santa Fe
December
Moderate crowds
High 40°F / low 21°F. Sunny most days.
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December, Moderate crowds, average high temperature 40 degrees Fahrenheit, average low temperature 21 degrees Fahrenheit. Sunny most days.
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January, Low crowds, average high temperature 39 degrees Fahrenheit, average low temperature 20 degrees Fahrenheit. Snow likely.
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43°
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February, Low crowds, average high temperature 43 degrees Fahrenheit, average low temperature 23 degrees Fahrenheit. Sunny most days.
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53°
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March, High crowds, average high temperature 53 degrees Fahrenheit, average low temperature 30 degrees Fahrenheit. Sunny most days.
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April, Low crowds, average high temperature 61 degrees Fahrenheit, average low temperature 37 degrees Fahrenheit. Sunny most days.
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May, Moderate crowds, average high temperature 70 degrees Fahrenheit, average low temperature 45 degrees Fahrenheit. Sunny most days.
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June, Moderate crowds, average high temperature 81 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
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July, High crowds, average high temperature 83 degrees Fahrenheit, average low temperature 60 degrees Fahrenheit. Sunny most days.
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August, High crowds, average high temperature 81 degrees Fahrenheit, average low temperature 58 degrees Fahrenheit. Sunny most days.
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September, Moderate crowds, average high temperature 75 degrees Fahrenheit, average low temperature 52 degrees Fahrenheit. Sunny most days.
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October, High crowds, average high temperature 63 degrees Fahrenheit, average low temperature 40 degrees Fahrenheit. Sunny most days.
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November, Low crowds, average high temperature 51 degrees Fahrenheit, average low temperature 29 degrees Fahrenheit. Sunny most days.
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Monthly weather averages (˚F)

Top landmarks in Guadalupe District

Santa Fe Railyard

4.3/5 (880 reviews)
If you want to give your credit card some exercise, head out to Santa Fe Railyard in Downtown Santa Fe. Hotels.com travelers also like the art galleries, cathedral, and museums in the area. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. Splash some more cash at Santa Fe Farmers Market.
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Santuario De Nuestra Senora de Guadalupe

If you're planning a bit of sightseeing head to Santuario De Nuestra Senora de Guadalupe— just one of the monuments in Downtown Santa Fe. Why not live the cultural experience and visit the museums, art galleries, and cathedral in the area— your sightseeing tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
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Check out reviews of Guadalupe District hotels guests love

Hotel Santa Fe

Hotel Santa Fe

10/10 Excellent
"Lovely room, wonderful staff. "
Heather 1-night trip
Posted 9 hours ago
Hotel Santa Fe

Frequently asked questions

Is Guadalupe District expensive to stay in?
You can find great hotels from $82 in Guadalupe District to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Guadalupe District hotels?
Discover great deals on hotels in Guadalupe District with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Guadalupe District hotels.
Can I receive a refund if I cancel my Guadalupe District hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Guadalupe District hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Guadalupe District?
You're spoilt for choice with 64 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Guadalupe District makes it easy to explore Santa Fe, including the neighborhoods of Downtown Santa Fe and Historic Eastside.
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