Hotels in Southeast Missouri

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Check prices for these dates

Tonight
24 Mar - 25 Mar
Tomorrow
25 Mar - 26 Mar
This weekend
28 Mar - 30 Mar
Next weekend
4 Apr - 6 Apr

Where to stay in Southeast Missouri?

Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1007)
The price is HK$734
HK$828 total
includes taxes & fees
30 Mar - 31 Mar
Drury Plaza Hotel Cape Girardeau Conference Center
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (374)
The price is HK$554
HK$615 total
includes taxes & fees
20 Apr - 21 Apr
Quality Inn Charleston - Sikeston
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1006)
The price is HK$769
HK$885 total
includes taxes & fees
30 Mar - 31 Mar
Drury Inn & Suites Sikeston, MO
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
The price is HK$801
HK$903 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:4 Apr - 6 Apr

Image gallery for OYO Malden Airport Inn

Reception

OYO Malden Airport Inn

2.5 star property
Malden
8.4/10Very good (39 reviews)
Member Price available
Price is HK$477
per night
HK$1,033 total
includes taxes & fees
OYO Malden Airport Inn

Image gallery for Microtel Inn & Suites by Wyndham Sainte Genevieve

Premium bedding, individually furnished, desk, laptop workspace

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
Ste Genevieve
8.8/10Excellent (557 reviews)
15% off
Price is HK$723
per night
HK$1,615 total
includes taxes & fees
Microtel Inn & Suites by Wyndham Sainte Genevieve

Image gallery for La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2.5 star property
Jackson
9.0/10Wonderful (519 reviews)
15% off
Price is HK$965
per night
HK$2,088 total
includes taxes & fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Image gallery for Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Exterior

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 star property
De Soto
9.4/10Exceptional (139 reviews)
25% off
Price is HK$1,131
per night
HK$2,625 total
includes taxes & fees
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Top landmarks in Southeast Missouri

Elephant Rocks State Park

Elephant Rocks State Park

Elephant Rocks State Park is 5.3 mi (8.5 km) from central Ironton, why not stop by during your stay?

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Elephant Rocks State Park
Lake Wappapello

Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

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Lake Wappapello
Echo Bluff State Park

Echo Bluff State Park

You can take time to visit Echo Bluff State Park during your travels to Salem. While you're in the area, stroll along the riverfront.

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Echo Bluff State Park

Learn more about Southeast Missouri

Southeast Missouri, well known for its wineries and riverfront, features attractions such as K Bridge Recreation Area and Lake Wappapello State Park. This family-friendly city has something for everyone including its university life, restaurants and sights like Clearwater Lake and Lake Wappapello.

See all hotels in Southeast Missouri

Frequently asked questions

Can I book a refundable accommodation option in Southeast Missouri?
If you want the flexibility to change your plans to Southeast Missouri, most hotels offer refundable* rates that you can book. You can see this accommodation by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Southeast Missouri if I want a holiday rental instead of a hotel?
If you’re looking for a good alternative to a hotel, look over our selection of 129 holiday homes. In addition, there are 46 apartments and 7 condos.
Why should I book my Southeast Missouri hotel with Hotels.com?
There are plenty of reasons to book your Southeast Missouri travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.