5 Star Hotels in Santa Cruz
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
5 Star Hotels in Santa Cruz

Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
9.0 out of 10, Wonderful, (191)
The price is HK$933
HK$933 total
23 Aug - 24 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top neighbourhoods in Santa Cruz
Top landmarks in Santa Cruz
Plaza 24 de Septiembre

Plaza 24 de Septiembre
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre – just one of the monuments in central Santa Cruz.
San Lorenzo Cathedral

San Lorenzo Cathedral
Learn about the local history of Santa Cruz when you take a trip to San Lorenzo Cathedral. While in the area, you can find time to visit its shops.
Keep exploring
Keep exploring
- Landmarks
- Star Rating
- Accommodation Types
- Theme
- Top Cities in Bolivia
- More Hotels
- Most popular destinations
- Santa Cruz Hotels with Parking
- Santa Cruz Hotels with Free Breakfast
- Santa Cruz Hotels with a Pool
- Santa Cruz Business Hotels
- Santa Cruz Family Hotels
- Santa Cruz Hotels with a Gym
- Santa Cruz Resorts & Hotels with Spas
- Santa Cruz Pet-friendly Hotels
- Santa Cruz Cheap Hotels
- Santa Cruz Hotels with Kitchens
- Santa Cruz Luxury Hotels
- HOTEL OSHO
- Hotel Puerta del Rey
- Senses Boutique Hotel
- Terranova Suites
- Equipetrol Suites Apart Hotel
- Swissôtel Santa Cruz De La Sierra
- Alfonsina Hotel Boutique by Inboccaluppo
- Hotel Arenal
- Buganvillas Hotel Suites & Spa
- Casa Vida
- Cosmopolitano Hotel Boutique
- Hotel Continental Park
- Casa Por Temporadas
- Hotel BY Armonia SCZ
- Radisson Hotel Santa Cruz
- Prince Hotel
- Yotau All Suites Hotel
- Urban Suites Apart Hotel
- Hotel Misional
- Apart Hotel Toborochi
- Posada Express by Hospedarte
- Santos Apartamentos
- Hotel Libertador Simon Bolivar
- Buena Vista Rental House
- Hotel Canciller
- Hotel Viru Viru II
- Apartamentos ARTECI
- Senses Centro
- Hotel Las Palmas
Most popular destinations
Hotels
- The Westin Grand Munich
- Hotels in French Quarter
- ibis Geneve Centre Nations
- MGH Mitsui Garden Hotel Taipei Zhongxiao
- Hotels in Hong Kong SAR
- Hôtel Le Dauphin
- HOTEL GRACERY Osaka Namba
- Hyatt Regency Hong Kong, Tsim Sha Tsui
- Hotel Fuji Tatsugaoka
- The Fullerton Ocean Park Hotel Hong Kong
- ibis Hong Kong Central And Sheung Wan
- Fraser Residence Nankai Osaka
- Four Points by Sheraton Phuket Patong Beach Resort
- Motto by Hilton New York City Chelsea
- Santhiya Koh Chang Resort
- RYSE, Autograph Collection Seoul by Marriott
- Splash Beach Resort, Mai Khao, Phuket
- Next Hotel Melbourne, Curio Collection by Hilton
- Hotels in Perth
- Boxtel at Suvarnabhumi Airport
- Hotel COZi Harbour View
- Hotels in Ginzan Onsen
- Fairfield Inn & Suites Charleston North/Ashley Phosphate
- Four Points Flex by Sheraton London Shoreditch East
- Shiretoko Noble Hotel
- Smile 73 Hotel
- Porto Seguro Eco Bahia Hotel
- Nina Hotel Kowloon East
- Tosei Hotel Cocone Ueno Okachimachi