Del Cerrillo's cobblestone streets reveal San Cristóbal's soul through colorful colonial buildings and Indigenous artisan workshops. Tzotzil weavers create vibrant textiles while visitors explore the Ex-Convent of Santo Domingo and Na Bolom Cultural Museum. From this elevated neighborhood, you'll catch breathtaking views of the Chiapas highlands while stepping back into the 16th century. Family-run comedores serve authentic Chiapanecan dishes like tamales de dulce for budget-friendly prices. The neighborhood is primarily pedestrian-friendly, with most attractions accessible through pleasant 10-15 minute walks to central San Cristóbal.

De La Merced offers a genuine dive into San Cristóbal de las Casas' cultural heart. This neighborhood features a 16th-century colonial church where Tzotzil and Tzeltal vendors display colorful textiles and amber jewelry at the Mercado Municipal. Visitors discover the Amber Museum, Regional Costume Museum, and centuries-old churches showcasing rich Indigenous Maya heritage along cobblestone streets. Family-run comedores serve authentic Chiapanecan dishes while local artisans sell hand-woven huipiles and ceremonial masks at reasonable prices. The neighborhood is best explored on foot, with most attractions just a 10-15 minute walk from the main plaza. Small posadas provide simple but charming accommodations for travelers seeking cultural immersion.

De Guadalupe bursts with Indigenous Mayan culture where hand-woven textiles in brilliant reds and blues catch the afternoon light. Cobblestone streets wind uphill past colonial churches and vibrant markets selling traditional crafts. The rhythmic clacking of backstrap looms fills artisan workshops as Tzotzil women create intricate huipiles, offering travelers an authentic glimpse into local traditions. Family-run comedores serve traditional Chiapanecan fare like tamales de dulce for incredibly budget-friendly prices. Traditional guesthouses and family homestays offer basic accommodations with high host interaction. Getting around requires sturdy shoes for steep streets, with colectivos providing irregular service to the city center.

Santa Lucía captivates visitors with its vibrant Indigenous Mayan culture and colonial charm. Wander cobblestone streets lined with colorful adobe homes where artisans create stunning textiles and amber jewelry right before your eyes. The neighborhood centers around its weathered stone church, while the Santo Domingo Handicraft Market offers authentic treasures that tell stories of generations past. Family-run comedores serve delicious Chiapanecan dishes like tamales de dulce for just a few dollars. Most visitors explore on foot despite the steep terrain, as the neighborhood sits uphill about 15 minutes from downtown San Cristóbal. The area quiets down after sunset, offering a peaceful glimpse into traditional Maya community life.